Methyl indole-5-carboxylate
Names
[ CAS No. ]:
1011-65-0
[ Name ]:
Methyl indole-5-carboxylate
[Synonym ]:
Indole-5-carboxylic acid,methyl ester
Methyl 1H-indole-5-carboxylate
1H-Indole-5-carboxylic acid, methyl ester
MFCD00153023
Indole-5-carboxylic Acid Methyl Ester
Methyl indole-5-carboxylate
Chemical & Physical Properties
[ Density]:
1.3±0.1 g/cm3
[ Boiling Point ]:
331.7±15.0 °C at 760 mmHg
[ Melting Point ]:
126-128 °C(lit.)
[ Molecular Formula ]:
C10H9NO2
[ Molecular Weight ]:
175.184
[ Flash Point ]:
154.4±20.4 °C
[ Exact Mass ]:
175.063324
[ PSA ]:
42.09000
[ LogP ]:
2.58
[ Vapour Pressure ]:
0.0±0.7 mmHg at 25°C
[ Index of Refraction ]:
1.639
[ Storage condition ]:
Refrigerator
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Eur. J. Med. Chem. 64 , 498-511, (2013)
This report describes the synthesis, and in vitro and in vivo antimalarial evaluations of certain ester-modified neocryptolepine (5-methyl-5H-indolo[2,3-b]quinoline) derivatives. The modifications wer...
Anticancer activity of MPT0E028, a novel potent histone deacetylase inhibitor, in human colorectal cancer HCT116 cells in vitro and in vivo.PLoS ONE 7(8) , e43645, (2012)
Recently, histone deacetylase (HDAC) inhibitors have emerged as a promising class of drugs for treatment of cancers, especially subcutaneous T-cell lymphoma. In this study, we demonstrated that MPT0E0...
Copper-catalyzed cross dehydrogenative coupling reactions of tertiary amines with ketones or indoles.Org. Lett. 12 , 5214, (2010)
A novel cross dehydrogenative coupling (CDC) reaction of N,N-dimethylanilines with methyl ketones by cooperative copper and aminocatalysis has been developed, which leads to the formation of β-arylami...