2-Benzylpyridine
Names
[ CAS No. ]:
101-82-6
[ Name ]:
2-Benzylpyridine
[Synonym ]:
2-Benzyl-pyridine
2-PHENYLPYRIDYLMETHANE
2-benzyl-pyridin
2-benzylpridine
Pyridine, 2-benzyl-
Pyridine, 2- (phenylmethyl)-
2-Benzylpyridine
MFCD00006352
benzyl-2-pyridine
2-(PHENYLMETHYL)PYRIDINE
CDD 3529
EINECS 202-979-1
bpmo
Pyridine, 2-(phenylmethyl)-
Pyridine,2-benzyl
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
276.0±0.0 °C at 760 mmHg
[ Melting Point ]:
8-10 °C(lit.)
[ Molecular Formula ]:
C12H11N
[ Molecular Weight ]:
169.222
[ Flash Point ]:
125.0±0.0 °C
[ Exact Mass ]:
169.089142
[ PSA ]:
12.89000
[ LogP ]:
2.71
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.576
[ Water Solubility ]:
insoluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- US2620000
- CHEMICAL NAME :
- Pyridine, 2-benzyl-
- CAS REGISTRY NUMBER :
- 101-82-6
- BEILSTEIN REFERENCE NO. :
- 0115875
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C12-H11-N
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1500 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Cardiac - pulse rate increase, without fall in BP
- REFERENCE :
- AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 227,129,1955
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H319
[ Precautionary Statements ]:
P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
S26-S37/39
[ RIDADR ]:
2810
[ WGK Germany ]:
3
[ RTECS ]:
US2620000
[ Packaging Group ]:
I; II; III
[ Hazard Class ]:
6.1
[ HS Code ]:
29333999
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933399090
[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Org. Lett. 16(7) , 2050-3, (2014)
The direct α-methylenation of benzylpyridines was achieved using N,N-dimethylacetamide (DMA) as a one-carbon source under copper catalysis. An intermediary species was detected at an early stage, and ...
Ruthenium(II) complexes of 2-benzoylpyridine-derived thiosemicarbazones with cytotoxic activity against human tumor cell lines.Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 69(4) , 1073-6, (2008)
Reaction of [RuCl(3)(dppb)H(2)O] (dppb=1,4 bis(diphenylphospine)butane) with 2-benzoylpyridine thiosemicarbazone (H2Bz4DH) and its N(4)-methyl (H2Bz4M) and N(4)-phehyl (H2Bz4Ph) derivatives gave [RuCl...