Lanthanum(III) chloride
Names
[ CAS No. ]:
10099-58-8
[ Name ]:
Lanthanum(III) chloride
[Synonym ]:
lanthanum chloride
Lanthanum trichloride
EINECS 233-237-5
lanthanum(III) chloride
MFCD00011068
Chemical & Physical Properties
[ Density]:
3.84 g/mL at 25ºC
[ Boiling Point ]:
1812ºC
[ Melting Point ]:
860 ºC
[ Molecular Formula ]:
Cl3La
[ Molecular Weight ]:
245.264
[ Flash Point ]:
1000ºC
[ Exact Mass ]:
243.812912
[ LogP ]:
2.06850
[ Stability ]:
Stability
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- OE4375000
- CHEMICAL NAME :
- Lanthanum chloride
- CAS REGISTRY NUMBER :
- 10099-58-8
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 17
- MOLECULAR FORMULA :
- Cl3-La
- MOLECULAR WEIGHT :
- 245.26
- WISWESSER LINE NOTATION :
- LA G3
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4184 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 106 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 121 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2424 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 18 mg/kg
- TOXIC EFFECTS :
- Liver - other changes
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 148 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 129 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - food intake (animal)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Amphibian - frog
- DOSE/DURATION :
- 694 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 112 mg/kg
- SEX/DURATION :
- female 12 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 112 mg/kg
- SEX/DURATION :
- female 6 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - other measures of fertility
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intratesticular
- DOSE :
- 5 mg/kg
- SEX/DURATION :
- male 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count) Reproductive - Paternal Effects - testes, epididymis, sperm duct
MUTATION DATA
- TEST SYSTEM :
- Mammal - domestic
- DOSE/DURATION :
- 5 mg/kg
- REFERENCE :
- IJEBA6 Indian Journal of Experimental Biology. (Publications & Information Directorate, CSIR, Hillside Rd., New Delhi 110 012, India) V.1- 1963- Volume(issue)/page/year: 11,143,1973 *** REVIEWS *** TOXICOLOGY REVIEW JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 54,663,1965
Safety Information
[ Symbol ]:
GHS05, GHS07, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H290-H317-H318-H411
[ Precautionary Statements ]:
P273-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
26-36
[ RIDADR ]:
UN3264
[ WGK Germany ]:
2
[ RTECS ]:
OE4375000
[ Packaging Group ]:
III
[ Hazard Class ]:
8
[ HS Code ]:
2846902300
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2846902300
Articles
Int. J. Biol. Macromol. 78 , 280-6, (2015)
The present study reports a novel approach for the preparation of polyamidoamine grafted chitosan beads (PAAGCB) via Michael addition followed by protonation of PAAGCB to get protonated PAAGCB (H(+)-P...
Sugar-metal ion interactions: the coordination behaviors of lanthanum with erythritol.Carbohydr. Res. 361 , 12-8, (2012)
Three novel lanthanum chloride-erythritol complexes (LaCl(3)·C(4)H(10)O(4)·5H(2)O (LaE(I)), LaCl(3)·C(4)H(10)O(4)·3H(2)O (LaE(II)), and LaCl(3)·1.5C(4)H(10)O(4) (LaE(III)) were synthesized and charact...
Lanthanum induced primary neuronal apoptosis through mitochondrial dysfunction modulated by Ca²⁺ and Bcl-2 family.Biol. Trace Elem. Res. 152(1) , 125-34, (2013)
As a representative element of lanthanide, lanthanum has been widely used in various fields and eventually entered environment and accumulated in human body. Epidemiological and experimental evidences...