KCNQ1 activator-1

Names

[ Name ]:
KCNQ1 activator-1

Biological Activity

[Description]:

KCNQ1 activator-1 (compound 3) is a potent activator of KCNQ1 channel. KCNQ1 activator-1 has the potential for the research of long QT syndrome (LQTS)[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Membrane Transporter/Ion Channel >> Potassium Channel

[References]

[1]. Mattmann ME, et al. Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator. Bioorg Med Chem Lett. 2012;22(18):5936-5941.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₃N₃O₄S₂

[ Molecular Weight ]:
457.57

[ Flash Point ]:
312.4±37.0 °C(Predicted)

Related Compounds

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