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Ganoderenic acid B

Names

[ CAS No. ]:
100665-41-6

[ Name ]:
Ganoderenic acid B

[Synonym ]:
Ganoderenic acid B
Lanosta-8,20(22)-dien-26-oic acid, 3,7-dihydroxy-11,15,23-trioxo-, (3β,5ξ,7β)-
(3β,5ξ,7β)-3,7-Dihydroxy-11,15,23-trioxolanosta-8,20(22)-dien-26-oic acid

Biological Activity

[Description]:

Ganoderenic acid B is a lanostane-type triterpene isolated from Ganoderma lucidum. Ganoderenic acid B exhibits potent reversal effect on ABCB1-mediated multidrug resistance of HepG2/ADM cells to Doxorubicin[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Liu DL, et al. Ganoderma lucidum derived ganoderenic acid B reverses ABCB1-mediated multidrug resistance in HepG2/ADM cells. Int J Oncol. 2015 May;46(5):2029-38.

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
702.7±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C30H42O7

[ Molecular Weight ]:
514.650

[ Flash Point ]:
392.8±29.4 °C

[ Exact Mass ]:
514.293030

[ PSA ]:
128.97000

[ LogP ]:
2.39

[ Vapour Pressure ]:
0.0±5.0 mmHg at 25°C

[ Index of Refraction ]:
1.575


Related Compounds