BMS-593214

Names

[ Name ]:
BMS-593214

[Synonym ]:
unii-xd269g3o31
1ge

Biological Activity

[Description]:

BMS-593214 is an active site-directed factor (F) VIIa inhibitor. BMS-593214 shows antithrombotic and antihaemostatic properties. BMS-593214 is a direct competitive inhibitor of human FVIIa and a non-competitive inhibitor of Viia-activated substrate FX. BMS-593214 prevents electroinduced carotid artery thrombosis (AT) and wire induced vena cava thrombosis (VT)[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

[References]

[1]. Wong PC, et al. BMS-593214, an active site-directed factor VIIa inhibitor: enzyme kinetics, antithrombotic and antihaemostatic studies. Thromb Haemost. 2010 Aug;104(2):261-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₁H₂₇N₃O₄

[ Molecular Weight ]:
505.56400

[ Exact Mass ]:
505.20000

[ PSA ]:
128.66000

[ LogP ]:
6.45910

Related Compounds

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