MILRINONE LACTATE

Names

[ Name ]:
MILRINONE LACTATE

[Synonym ]:
2-Hydroxypropansäure--2-methyl-6-oxo-1,6-dihydro-3,4'-bipyridin-5-carbonitril(1:1)
UNII:9K8XR81MO8
Milrinone lactate
2-hydroxypropanoic acid,6-methyl-2-oxo-5-pyridin-4-yl-1H-pyridine-3-carbonitrile
2-Hydroxypropanoic acid - 2-methyl-6-oxo-1,6-dihydro-3,4'-bipyridine-5-carbonitrile (1:1)
Propanoic acid, 2-hydroxy-, compd. with 1,6-dihydro-2-methyl-6-oxo[3,4'-bipyridine]-5-carbonitrile (1:1)

Biological Activity

[Description]:

Milrinone lactate is a potent inotropic dilating agent. Milrinone lactate shows simultaneous positive inotropic and vasodilating activities. Milrinone lactate promotes reduction of SVR and PVR in patients with DCM and NYHA class III and IV of heart failure. Milrinone lactate has the potential for the research of cardiovascular function after cardiac surgery and in septic shock[1][2].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Others >> Others

[References]

[1]. Bregagnollo EA, et al. Assessment of inotropic and vasodilating effects of milrinone lactate in patients with dilated cardiomyopathy and severe heart failure. Arq Bras Cardiol. 1999 Feb;72(2):149-60.

[2]. Meyer S, et al. The role of milrinone in children with cardiovascular compromise: review of the literature. Wien Med Wochenschr. 2011 Apr;161(7-8):184-91.

Chemical & Physical Properties

[ Boiling Point ]:
448.7ºC at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₅N₃O₄

[ Molecular Weight ]:
301.297

[ Flash Point ]:
225.2ºC

[ Exact Mass ]:
301.106262

[ PSA ]:
127.07000

[ LogP ]:
1.06878

[ Vapour Pressure ]:
3.04E-08mmHg at 25°C

Related Compounds

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