D-(+)-Carnitine hydrochloride

Names

[ Name ]:
D-(+)-Carnitine hydrochloride

[Synonym ]:
3-carboxy-2-hydroxy-n,n,n-trimethyl-,chloride,(s)-1-propanaminiu
(2R)-3-carboxy-2-hydroxy-N,N,N-trimethylpropan-2-aminium chloride
CARNITINE HYDROCHLORIDE, (+)-
d-Carnitine chloride
(+)-(3-Carboxy-2-hydroxypropyl)trimethylammonium chloride
Vitamine BT
1-Propanaminium, 3-carboxy-2-hydroxy-N,N,N-trimethyl-, chloride, (2S)- (1:1)
D-Carnitine hydrochloride
[3H]-L-(-)-Carnitine hydrochloride
(2S)-3-Carboxy-2-hydroxy-N,N,N-trimethyl-1-propanaminium chloride
S-Cartininehydrochloride
1-Propanaminium,3-carboxy-2-hydroxy-N,N,N-trimethyl-,chloride,(2S)
(S)-Carnitine hydrochloride
(+)-CARNITINE HYDROCHLORIDE
1-Propanaminium,3-carboxy-2-hydroxy-N,N,N-trimethyl-,chloride,(S)
(2S)-3-Carboxy-2-hydroxy-N,N,N-trimethylpropan-1-aminium chloride
R-(-)-carnitine hydrochloride
1-Propanaminium,3-carboxy-2-hydroxy-N,N,N-trimethyl-,chloride,(2S)-(9CI)

Biological Activity

[Description]:

L-carnitine hydrochloride ((S)-Carnitine Hydrochloride) has been used to study sulfur factor transporter SLC22A4 and carnitine transporter slc22a5 in ergot. L-Carnitine hydrochloride is also used to get palmitic acid into mitochondria[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others

[References]

[1]. Horvath GA, et al. Newborn screening for MCAD deficiency: experience of the first three years in British Columbia, Canada. Can J Public Health. 2008 Jul-Aug;99(4):276-80.

[2]. Leenders JJ, et al. Regulation of cardiac gene expression by KLF15, a repressor of myocardin activity. J Biol Chem. 2010 Aug 27;285(35):27449-56.

Chemical & Physical Properties

[ Molecular Formula ]:
C₇H₁₆ClNO₃

[ Molecular Weight ]:
197.660

[ Exact Mass ]:
197.081863

[ PSA ]:
57.53000

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BP2979120

CHEMICAL NAME :: Ammonium, (3-carboxy-2-hydroxypropyl)trimethyl-, chloride, (+)-

CAS REGISTRY NUMBER :: 10017-44-4

LAST UPDATED :: 198912

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C7-H15-N-O3.Cl

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5700 mg/kg

TOXIC EFFECTS :: Behavioral - convulsions or effect on seizure threshold Behavioral - fluid intake Lungs, Thorax, or Respiration - cyanosis

REFERENCE :: ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. Volume(issue)/page/year: 3,28,1959

Safety Information

[ HS Code ]:
2923900090

Customs

[ HS Code ]: 2923900090

[ Summary ]:
2923900090 other quaternary ammonium salts and hydroxides。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%