Pimefylline
Names
[ CAS No. ]:
10001-43-1
[ Name ]:
Pimefylline
[Synonym ]:
Pimefylline [INN]
7-(ss-3'-Picolylaminoaethyl)-theophyllin
Pimefyllinum [INN-Latin]
Pimefilina [INN-Spanish]
Pimefylline
Pimephylline
Pimefyllin
1,3-dimethyl-7-[2-(pyridin-3-ylmethyl-amino)-ethyl]-3,7-dihydro-purine-2,6-dione
7-(2-((3-Pyridylmethyl)amino)ethyl)theophylline
Chemical & Physical Properties
[ Density]:
1.37g/cm3
[ Boiling Point ]:
575.6ºC at 760mmHg
[ Molecular Formula ]:
C15H18N6O2
[ Molecular Weight ]:
314.34200
[ Flash Point ]:
301.9ºC
[ Exact Mass ]:
314.14900
[ PSA ]:
86.74000
[ LogP ]:
0.00940
[ Vapour Pressure ]:
3E-13mmHg at 25°C
[ Index of Refraction ]:
1.682
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XH6494000
- CHEMICAL NAME :
- Theophylline, 7-(2-((3-pyridylmethyl)amino)ethyl)-
- CAS REGISTRY NUMBER :
- 10001-43-1
- BEILSTEIN REFERENCE NO. :
- 1167438
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C15-H18-N6-O2
- MOLECULAR WEIGHT :
- 314.39
- WISWESSER LINE NOTATION :
- T56 BN DN FNVNVJ F1 H1 B2M1- CT6NJ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PAHEAA Pharmaceutica Acta Helvetiae. (Schweizerische Apothekerzeitung, Postfach 3006, CH3000 Bern, 7, Switzerland) V.1- 1926- Volume(issue)/page/year: 48,133,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 402 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PAHEAA Pharmaceutica Acta Helvetiae. (Schweizerische Apothekerzeitung, Postfach 3006, CH3000 Bern, 7, Switzerland) V.1- 1926- Volume(issue)/page/year: 48,133,1973
Safety Information
[ HS Code ]:
2933990090
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%