4-nitrobenzylbromide
Names
[ CAS No. ]:
100-11-8
[ Name ]:
4-nitrobenzylbromide
[Synonym ]:
α-Bromoparanitrotoluene
1-(Bromomethyl)-4-nitrobenzene
Benzene, 1- (bromomethyl)-4-nitro-
Toluene, α-bromo-4-nitro-
α-Bromo-4-nitrotoluene
α-Bromo-p-nitrotoluene
4-nitrobenzylbromide
MFCD00007373
EINECS 202-820-6
Benzene, 1-(bromomethyl)-4-nitro-
Toluene, α-bromo-p-nitro-
4-Nitrobenzyl bromide
Chemical & Physical Properties
[ Density]:
1.7±0.1 g/cm3
[ Boiling Point ]:
304.2±17.0 °C at 760 mmHg
[ Melting Point ]:
98 °C
[ Molecular Formula ]:
C7H6BrNO2
[ Molecular Weight ]:
216.032
[ Flash Point ]:
137.8±20.9 °C
[ Exact Mass ]:
214.958176
[ PSA ]:
45.82000
[ LogP ]:
2.65
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.612
[ Stability ]:
Stable. Incomaptible with bases, amines, oxidizing agents, alcohols. May be moisture sensitive. Corrodes steel.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XS7967000
- CHEMICAL NAME :
- Toluene, alpha-bromo-p-nitro-
- CAS REGISTRY NUMBER :
- 100-11-8
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C7-H6-Br-N-O2
- MOLECULAR WEIGHT :
- 216.05
- WISWESSER LINE NOTATION :
- WNR D1E
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 56 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Unscheduled DNA synthesis
- TEST SYSTEM :
- Rodent - rat Liver
- DOSE/DURATION :
- 10 umol/L
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 3,11,1981
Safety Information
[ Symbol ]:
GHS05
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H314
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
C:Corrosive
[ Risk Phrases ]:
R34
[ Safety Phrases ]:
S26-S36/37/39-S45
[ RIDADR ]:
UN 3261 8/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
XS7967000
[ Packaging Group ]:
II
[ Hazard Class ]:
8
[ HS Code ]:
29049085
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2904909090
[ Summary ]:
HS:2904909090 sulphonated, nitrated or nitrosated derivatives of hydrocarbons, whether or not halogenated VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
Articles
Ital. Gen. Rev. Dermatol. 15(2) , 107-12, (1978)
A case of occupational contact dermatitis in a female chemical pharmaceutical laboratory researcher is described. The allergological investigation revealed a state of sensitization to three mono-nitro...
Synthesis of p, p'-divinylazobenzene.Di Yi Jun Yi Da Xue Xue Bao 23(3) , 273-6, (2003)
To synthesize p, p'-divinylazobenzene (DVAB).Wittig reagent was initially synthesized using P-nitrobenzyl bromide and triphenylphosphine, followed by reaction with formaldehyde to produce p-nitro styr...
Allergic contact dermatitis from para-nitrobenzyl bromide.Contact Dermatitis 38(4) , 232, (1998)