Gold activation of nitriles: Catalytic hydration to amides

RS Ramon, N Marion, SP Nolan

Index: Ramon, Ruben S.; Marion, Nicolas; Nolan, Steven P. Chemistry - A European Journal, 2009 , vol. 15, # 35 p. 8695 - 8697

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Citation Number: 122

Abstract

In the last few years, homogeneous gold catalysis has become a field of intense activity.[1] This is due in part to the high versatility of goldACHTUNGTRENNUNG (I/III) catalysts that can act both as σand π-Lewis acids, which has notably permitted the activation of a wide diversity of functional groups (Scheme1, top). Typically, carbon-based unsaturated systems (ie, alkenes, allenes, and alkynes) are activated via π-coordination, whereas heteroatom- ...

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