Isolation and Biochemical Characterization of a New Topoisomerase I Inhibitor from Ocotea l eucoxylon

BN Zhou, RK Johnson, MR Mattern…

Index: Vecchietti; Casagrande; Ferrari; Severini Ricca Farmaco, Edizione Scientifica, 1979 , vol. 34, # 10 p. 829 - 840

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Citation Number: 59

Abstract

... Volume: Page: ... 10-OCH3, 3.81 (3H, s), 55.71, C-10, H-11. ... To evaluate the mechanistic similarity between dicentrinone and camptothecin in mammalian cells, its toxic potency was determined against wild-type and camptothecin-resistant P-388 mouse leukemia ...