New β-adrenoceptor-blocking agents derived from dicyclopropyl ketone oxime: influence of amino substituents on in vivo activity

…, A Bouzoubaa, M Blanc, G Leclerc

Index: Amlaiky; Leclerc; Decker; Schwartz European Journal of Medicinal Chemistry, 1983 , vol. 18, # 5 p. 437 - 439

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Citation Number: 5

Abstract

Abstract A series of oximinopropanolamines derived from dicyclopropyl ketone, in which the amine substituents were alkyl, cycloalkyl, aryl and aralkyl groups, has been synthesized. The β-adrenergic blocking properties were determined on anaesthetized rats. Two N-aralkyl