Tetrahedron letters

Clean and selective oxidation of aromatic alcohols using silica-supported Jones' reagent in a pressure-driven flow reactor

C Wiles, P Watts, SJ Haswell

Index: Wiles, Charlotte; Watts, Paul; Haswell, Stephen J. Tetrahedron Letters, 2006 , vol. 47, # 30 p. 5261 - 5264

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Citation Number: 50

Abstract

By exploiting the high surface to volume ratio obtained within continuous flow reactors, we are able to oxidise selectively an array of primary alcohols to either the aldehyde or carboxylic acid, depending on the flow rates employed, demonstrating a degree of reaction control unattainable in traditional stirred reactors.