Synthesis of tetrazolo [1, 5-a] quinoxaline based azetidinones & thiazolidinones as potent antibacterial & antifungal agents

…, R Azim, A Khurana, M Shaquiquzzaman…

Index: Kumar, Shiv; Khan; Alam, Ozair; Azim, Rizwan; Khurana, Atul; Shaquiquzzaman; Siddiqui, Nadeem; Ahsan, Waquar Bulletin of the Korean Chemical Society, 2011 , vol. 32, # 7 p. 2260 - 2266

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Citation Number: 6

Abstract

Abstract 4-Chlorotetrazolo [1, 5-a] quinoxaline (III) was synthesized by azide (2+ 3) cycloaddition of 2, 3-dichloroquinoxaline (II). Compound (III) on further refluxing with hydrazine hydrate furnished 4-hydrazinotetrazolo [1, 5-a] quinoxaline (IV). Further refluxing of (IV) with different aromatic aldehydes in methanol yielded corresponding Schiff's bases V (aj). Various 4-aminotetrazolo [1, 5-a] quinoxaline based azetidinones VII (aj) were ...