Tetrahedron

Efficient access to (1H)-isoindolin-1-one-3-carboxylic acid derivatives by orthopalladation and carbonylation of methyl arylglycinate substrates

S Nieto, FJ Sayago, P Laborda, T Soler, C Cativiela…

Index: Nieto, Sonia; Sayago, Francisco J.; Laborda, Pedro; Soler, Tatiana; Cativiela, Carlos; Urriolabeitia, Esteban P. Tetrahedron, 2011 , vol. 67, # 23 p. 4185 - 4191

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Citation Number: 25

Abstract

Abstract The orthopalladation of methyl arylglycinate derivatives has been studied. The reaction proceeds efficiently for different electron-withdrawing and electron-releasing substituents at the aryl ring. The carbonylation of the orthopalladated complexes affords, ...

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