Cyclocondensation of Hydroxylamine with 1, 3??Bis (het) arylmonothio 1, 3??Diketones and 1, 3??Bis (het) aryl??3??(methylthio)??2??propenones: Synthesis of 3, 5??Bis (het) …
B Raghava, G Parameshwarappa…
Index: Raghava, Byregowda; Parameshwarappa, Gangajji; Acharya, Anand; Swaroop, Toreshettahally R.; Rangappa, Kanchugarakoppal S.; Ila, Hiriyakkanavar European Journal of Organic Chemistry, 2014 , vol. 2014, # 9 p. 1882 - 1892
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Citation Number: 12
Abstract
Abstract Efficient routes for the regioselective synthesis of 3, 5-bis (het) arylisoxazoles with complementary regioselectivity have been developed. The methods involve the cyclocondensation of hydroxylamine hydrochloride with either 1, 3-bis (het) aryl-monothio- substituted 1, 3-diketones 1 or with 3-methylthio-1, 3-bis (het) aryl-2-propenones 2 under various reaction conditions. In the first protocol, diketones 1 were treated with ...
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