Amplification-Free Detection of Circulating microRNA Biomarkers from Body Fluids Based on Fluorogenic Oligonucleotide-Templated Reaction between Engineered …

…, A Zivi, N Rama, CL Bevan, S Ladame

Index: Sleiman, Mazen Haj; Ladame, Sylvain Chemical Communications, 2014 , vol. 50, # 40 p. 5288 - 5290

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Abstract

Highly abundant in cells, microRNAs (or miRs) play a key role as regulators of gene expression. A proportion of them are also detectable in biofluids making them ideal noninvasive biomarkers for pathologies in which miR levels are aberrantly expressed, such