Journal of heterocyclic chemistry

Synthesis of crown ethers containing a thiazole subcyclic unit

HS Kim, IC Kwon, JH Choi

Index: Kim, Hong-Seok; Kwon, II-Chun; Choi, Jun-Hyeak Journal of Heterocyclic Chemistry, 1999 , vol. 36, # 5 p. 1285 - 1289

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Citation Number: 6

Abstract

Abstract Crown ethers containing a thiazole subcyclic unit are prepared from the reactions of 1, 3-bis [2 (4-hydroxymethylthiazoyl)] benzene with di-p-tosylates of corresponding di, tri, tetra, pentaethylene glycols in the presence of potassium hydride. However, if the cavity size in the ring system is small,[2+ 2] cyclization adduct also is formed.

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