Brønsted-acid-catalyzed coupling of electron-rich arenes with substituted allylic and secondary benzylic alcohols
J Le Bras, J Muzart
Index: Le Bras, Jean; Muzart, Jacques Tetrahedron, 2007 , vol. 63, # 33 p. 7942 - 7948
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Citation Number: 74
Abstract
Direct arylation of allylic and benzylic alcohols under conditions leading to water as the only by-product would represent a green process. Surprisingly, such a simple approach has not been described with electron-rich arenes, probably because homogeneous Brønsted acids were not found to be effective catalysts in Friedel–Crafts reactions, in the past. 19 and 20 However, while this work was in progress, Sanz et al. have reported a similar procedure in organic ...
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