Substituted tetralins I: Synthesis and analgesic activities of some 2??Aminotetralins

…, AP Parulkar, DJ Gusseck, LJ Anderson…

Index: Martin; Parulkar; Gusseck; Anderson; Grunewald; White Journal of pharmaceutical sciences, 1969 , vol. 58, # 3 p. 340 - 347

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Citation Number: 12

Abstract

Abstract The synthesis of nine 4, 4-dimethyl-2-aminotetralins is described and their analgesic potencies are reported. One of the series, N, N-dimethyl-4, 4-dimethyl-2- naphthylamine, has an analgesic potency about two and one-half times that of codeine or meperidine.