A new and efficient route toward the preparation of diazo ketones using cyanuric chloride and diazomethane
DC Forbes, EJ Barrett, DL Lewis, MC Smith
Index: Forbes; Barrett; Lewis; Smith Tetrahedron Letters, 2000 , vol. 41, # 51 p. 9943 - 9947
Full Text: HTML
Citation Number: 34
Abstract
A new method for the preparation of diazo ketones has been developed. 2, 4, 6-Trichloro-1, 3, 5-triazine (cyanuric chloride) has been found to be an excellent coupling reagent allowing for the efficient transfer of diazomethane to a carboxylic acid. Preparation of diazo ketones using carboxylic acids and triazine reagents is considerably more convenient than classical diazo transfer protocols because water does not have to be stringently removed and the ...
Related Articles:
Aracyl triflates as derivatizing agents for biological betaines
[Happer, D. Alan R.; Hayman, Colin M.; Storer, Malina K.; Lever, Michael Australian Journal of Chemistry, 2004 , vol. 57, # 5 p. 467 - 472]
Preparation of New Dialkyl Benzene-, Biphenyl-, and Naphthalene-bis (α-oxoethanedithioates)
[Voss, Jurgen; Sarafidis, Abraam; Sawluk, Andrzej; Schmidt, Gunther; Adiwidjaja, Gunadi Phosphorus, Sulfur and Silicon and the Related Elements, 2010 , vol. 185, # 11 p. 2249 - 2276]
Aracyl triflates as derivatizing agents for biological betaines
[Happer, D. Alan R.; Hayman, Colin M.; Storer, Malina K.; Lever, Michael Australian Journal of Chemistry, 2004 , vol. 57, # 5 p. 467 - 472]
[Sezer, Oezkan; Anac, Olcay Helvetica Chimica Acta, 1994 , vol. 77, # 8 p. 2323 - 2334]
[Young, Jonathan R.; Huang, Song X.; Chen, Irene; Walsh, Thomas F.; DeVita, Robert J.; Wyvratt Jr., Matthew J.; Goulet, Mark T.; Ren, Ning; Lo, Jane; Yang, Yi Tien; Yudkovitz, Joel B.; Cheng, Kang; Smith, Roy G. Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 15 p. 1723 - 1727]