Tetrahedron Letters

Copper catalyzed Gomberg–Buchmann–Hey reaction using aryldiazonium tosylate

GU Chaturbhuj, KG Akamanchi

Index: Chaturbhuj, Ganesh U.; Akamanchi, Krishnacharya G. Tetrahedron Letters, 2011 , vol. 52, # 38 p. 4950 - 4953

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Citation Number: 10

Abstract

Abstract Copper catalyzed modification of Gomberg–Bachmann–Hey reaction to synthesize symmetrical/unsymmetrical biaryls via diazotization of anilines with p-TSA and NaNO 2 system at 50 C, in aromatic liquids as solvents and second partners was successfully developed. Aniline and 3-nitronaniline gave biphenyl and 3-nitrobiphenyl, respectively, with moderate yields. All para-substituted anilines gave comparatively higher yields while in ...

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