Phytotherapy Research 2004-02-01

Arjunetin from Terminalia arjuna as an insect feeding-deterrent and growth inhibitor.

D V Singh, M M Gupta, A K Tripathi, Veena Prajapati, S Kumar

Index: Phytother Res. 18(2) , 131-4, (2004)

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Abstract

Crude ethanolic extract of the stem bark of Terminalia arjuna (Combretaceae) and its three compounds namely arjunic acid, arjungenin and arjunetin were evaluated for antifeedant, growth inhibitory and oviposition-deterrent activities against a lepidopterous insect Spilarctia obliqua. The compound arjunetin showed highest growth inhibitory and feeding-deterrent properties with a growth inhibition (GI(50)) and feeding-inhibition (FD(50)) of 188.5 and 287.1 micro g/g diet respectively. Oviposition bioassays indicated no oviposition-deterrence in any of the compounds tested. The structure-activity relationship study indicated the importance of a glycosidation linkage in arjunetin.Copyright 2004 John Wiley & Sons, Ltd.