Arzneimittel-Forschung

[Chemotherapeutically active nitro compounds. 2nd communication: Nitrodiphenyl sulfones (author's transl)]

E Winkelmann, W Raether, WH Wagner

Index: Winkelmann,E. et al. Arzneimittel Forschung, 1976 , vol. 26, p. 1543 - 1547

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Citation Number: 8

Abstract

A number of new 4-nitro-4'-amino-diphenyl sulfones and related compounds were prepared and investigated as to their therapeutic activity. They showed a good systemic activity against tubercle bacilli (M. bovis, NMRI mouse) and plasmodia (P. berghei, NMRI mouse). The test results reveal that the 4-nitro-4'-amino-diphenyl sulfones possess a spectrum of activity similar to that of diamino-diphenyl sulfone (DDS). It is assumed that 4-nitro-4'- ...