Bioorganic & Medicinal Chemistry Letters
2009-01-01
1,2,3-Triazole derivatives as new cannabinoid CB1 receptor antagonists
Duen-Ren Hou, Safiul Alam, Ting-Chun Kuan, Mani Ramanathan, Tsung-Pang Lin, Ming-Shiu Hung
Index: Bioorg. Med. Chem. Lett. 19(3) , 1022-5, (2009)
Full Text: HTML
Abstract
Development of new 1,2,3-triazoles as effective and selective CB1 receptor antagonists (IC 50 = 11.6 ± 3.4 nM; CB2/CB1 > 1000) is reported.
Related Compounds
Related Articles:
New Tricks in Amino Acid Synthesis: Applications to Complex Natural Products.
2011-04-01
[ACS Symp. Ser. 1009 , 420-442, (2009)]
Synthesis and Antimicrobial Activity Evaluation of Novel 4-Thiazolidinones Containing a Pyrone Moiety. Nechak R, et al.
[Synth. Commun. , 1-11, (2014)]