Journal of Fluorine Chemistry

Studies in spiroheterocycles. Part XVI. Synthesis of new flourine-containing spiro-3-indoline derivatives

KC Joshi, A Dandia, S Sanan

Index: Joshi, Krishna C.; Dandia, Anshu; Sanan, Sangeeta Journal of Fluorine Chemistry, 1989 , vol. 44, p. 59 - 72

Full Text: HTML

Citation Number: 29

Abstract

Abstract The reaction of fluorinated phenylthioureas, with some new fluorine-containing 3-(2- oxocycloalkylidene) indol-2-ones (2) in ethanolic KOH medium, yielded a series of new fluorine containing 5′, 6′-cyclopenta-2′-thioxo-3′-phenyl spiro [3H-indole-3, 4′(3′ H)- pyrimidin]-2 (1H)-ones and 2′, 4′ a, 5′, 6′, 7′, 8′,-hexahydro-2′-thioxo-3′-phenyl spiro [3H-indole-3, 4′(3′ H)-quinazolin]-2 (1H)-ones in 55–68% yields. New fluorine- ...