The Journal of Organic Chemistry

Conjugate Addition of Disodiophenylacetate to Ethyl Cinnamate to Form erythro-and threo-4-Carbethoxy-2, 3-diphenylbutyric Acids

RB MEYER, CR HAUSER

Index: Meyer,R.B.; Hauser,C.R. Journal of Organic Chemistry, 1961 , vol. 26, p. 3183 - 3186

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Citation Number: 8

Abstract

Disodiophenylacetate, prepared from phenylacetic acid and two molecular equivalents of sodium amide in liquid ammonia, underwent conjugate addition to ethyl ciniiamate to form erythro-and threo-4-carbethovv-2, 3-diphenylbutyric acids in approvimately equal amounts. The configurations of these isomers were established by hj-drolysis and by esterification to the diacids and diethyl esters, respectively. The conjugate addition appeared to occur ...