Resolution and sensitivity aspects of ultrafast J-resolved 2D NMR spectra.

Patrick Giraudeau, Serge Akoka

Index: J. Magn. Reson. 190(2) , 339-45, (2008)

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Abstract

Recent ultrafast techniques enable nD NMR spectra to be obtained in a single scan. However, resolution enhancement in the ultrafast domain leads to important sensitivity losses and lineshape distortions. In order to understand better resolution and spatial encoding aspects of continuous phase-encoding schemes, a theoretical and experimental comparison of different excitation patterns is carried out. Molecular diffusion appears to be the main cause of signal-to-noise ratio decrease, and a multi-echo excitation scheme is proposed to limit its effects when a good resolution is needed. Results obtained on 2D J-resolved spectra are presented.