Chemistry Letters

Electronically Modified Polymer-supported Cinchona Phase-transfer Catalysts for Asymmetric Synthesis of. ALPHA.-Alkyl-. ALPHA.-amino Acid Derivatives

…, YJ Lee, H Song, M Cheng, S Jew, H Park, BS Jeong

Index: Shi, Qinghua; Lee, Yeon-Ju; Song, Hongrui; Cheng, Maosheng; Jew, Sang-Sup; Park, Hyeung-Geun; Jeong, Byeong-Seon Chemistry Letters, 2008 , vol. 37, # 4 p. 436 - 437

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Citation Number: 21

Abstract

Merrifield resin-supported hydrocinchonidinium salts containing particular functional groups that can participate in hydrogen bonding were prepared and evaluated as chiral phase- transfer catalysts using the asymmetric benzylation of glycine imine ester. These electronically modified Merrifield resin-supported phase-transfer catalysts generally provided better enantioselectivities compared to the unmodified ones.