1, 7??Octadiene??Assisted Tandem Multicomponent Cross??Enyne Metathesis (CEYM)??Diels–Alder Reactions: A Useful Alternative to Mori's Conditions

…, P Bello, J Miró, A Simón, C del Pozo

Index: Fustero, Santos; Bello, Paula; Miro, Javier; Simon, Antonio; Del Pozo, Carlos Chemistry - A European Journal, 2012 , vol. 18, # 35 p. 10991 - 10997

Full Text: HTML

Citation Number: 22

Abstract

Abstract The use of 1, 7-octadiene as an in situ source of ethylene led us to develop a novel multicomponent tandem cross-enyne metathesis (CEYM)-Diels–Alder reaction. The process can be considered a relay metathesis, in which the ethylene liberated in the ring-closing metathesis (RCM) of 1, 7-octadiene initiates the tandem sequence. Aliphatic, aromatic, and fluorinated alkynes and several dienophiles are compatible with the process, which is ...