Gas–Liquid Segmented Flow Microfluidics for Screening Pd??Catalyzed Carbonylation Reactions

…, AD Gee, NJ Long, AJ de Mello, R Vilar

Index: Gong, Xiuqing; Miller, Philip W.; Gee, Antony D.; Long, Nicholas J.; De Mello, Andrew J.; Vilar, Ramon Chemistry - A European Journal, 2012 , vol. 18, # 10 p. 2768 - 2772

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Citation Number: 20

Abstract

Chemical reactions that occur within nanoliter to microliter volumes demonstrate many advantages over traditional batch synthetic methods.[1–4] On the microscale, the inherent high surface area-to-volume ratios facilitate highly efficient heat transfer processes and rapid and controllable mixing regimes enhancing mass transport. Both factors act to significantly enhance product quality, reaction yields and analytical throughput. Reactions performed ...