Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 1989-07-01

[Inhibitory effect of inositol hexasulfate and inositol hexaphosphoric acid (phytic acid) on the proliferation of the human immunodeficiency virus (HIV) in vitro].

T Otake, H Shimonaka, M Kanai, K Miyano, N Ueba, N Kunita, T Kurimura

Index: Kansenshōgaku Zasshi. 63(7) , 676-83, (1989)

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Abstract

The monosaccharide substances inositol hexasulfate (IHS) and inositol hexaphosphoric acid (Phytic acid, IHP) were investigated for their antiviral effect on the human immunodeficiency virus (HIV) in vitro. In MT-4 cells IHS completely inhibited the cytopathic effect of HIV and the HIV specific antigen expression at a concentration of 1.67 mg/ml. IHP moderately inhibited both of HIV effects as mentioned above.


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