N-Allyl analogs of phencyclidine: chemical synthesis and pharmacological properties

…, A Amir, P Fuchs, SA Lee, EJ Holsztynska…

Index: Kalir; Teomy; Amir; Fuchs; Lee; Holsztynska; Rocki; Domino Journal of Medicinal Chemistry, 1984 , vol. 27, # 10 p. 1267 - 1271

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Citation Number: 5

Abstract

Results Chemistry. The synthesis of the N-allyl derivatives was carried out according to Scheme I.(Alky1amino) cyclohexanecarbonitriles (1 1) were prepared from cyclohexanone (S), alkylamine hydrochloride (9), and sodium cyanide (10). Their reaction with phenyllithium yielded