Phenothiazine derivatives: mono-oxygenated compounds

DF Houston, EB Kester, F DeEds

Index: Houston Journal of the American Chemical Society, 1949 , vol. 71, p. 395

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Citation Number: 24

Abstract

Phenothiazine (I) has been shown2 to have in vitm tuberculostatic action which is somewhat diminished in the presence of serum. The oxidized derivatives known as phenothiazone (11) and thionol (111) also showed a moderate inhibiting effect, and it was postulated that their lesser effectiveness might be connected with their decreased solubility in lipids. Compounds having