Phytochemistry

Ring-methyl hydroxylation of chlortoluron by an inducible cytochrome P450-dependent enzyme from maize

R Fonné-Pfister, K Kreuz

Index: Fonne-Pfister, Raymonde; Kreuz, Klaus Phytochemistry (Elsevier), 1990 , vol. 29, # 9 p. 2793 - 2796

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Citation Number: 50

Abstract

Abstract An enzyme catalysing ring-methyl hydroxylation of the substituted phenylurea herbicide chlortoluron was detected in isolated microsomes from germinating maize. Chlortoluron hydroxylation was absolutely dependent on NADPH and molecular oxygen. The enzyme was inhibited by carbon monoxide in the presence of oxygen and this inhibition could be reversed by light. Several known inhibitors of cytochrome P450 enzymes ...