3, 3, 9, 9-Tetramethyl-1, 5, 7, 11-tetraoxaspiro [5.5] undecane as a reagent for protection of carbonyl compounds

…, M Bakavoli, A Shiri, H Eshghi, S Saberi

Index: Rahimizadeh, Mohammad; Bakavoli, Mehdi; Shiri, Ali; Eshghi, Hossein; Saberi, Sattar Journal of Chemical Research, 2008 , # 12 p. 704 - 706

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Citation Number: 4

Abstract

The protection of carbonyl groups as acetals or ketals and their subsequent regenerations is an important strategy in a multi-stage organic synthesis.l Numerous attempts to improve the efficiency of this process have been investigated and a number of strategies, such as the use of protic acids, Lewis acids, solid acids and ionic liquids as the catalyst, with 1,2- diols, 1,3-diols, 1,2-dithiols, 1,3-dithiols and orthoesters as the protecting reagents,2 have been reported. ...