Tetrahedron

Dimethylbut-2-ynedioate mediated esterification of acids via sp 3 C–N bond cleavage of benzylic tertiary amines

H Shen, X Lu, KZ Jiang, KF Yang, Y Lu, ZJ Zheng…

Index: Shen, Hao; Lu, Xing; Jiang, Ke-Zhi; Yang, Ke-Fang; Lu, Yixin; Zheng, Zhan-Jiang; Lai, Guo-Qiao; Xu, Li-Wen Tetrahedron, 2012 , vol. 68, # 43 p. 8916 - 8923

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Citation Number: 7

Abstract

A straightforward synthetic transformation of tertiary amines to the esterification of equimolar amounts of acids was demonstrated in this manuscript. The present protocol can be regarded as a straightforward synthetic transformation of tertiary amines to the esterification of equimolar amounts of acid. Moreover, the reaction is fundamentally new chemistry for the sp3 C–N bond cleavage coupled with esterification. The esterification reaction conditions ...

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