Tetrahedron letters

Titanium (IV) catalysis in the reduction of phosphine oxides

T Coumbe, NJ Lawrence, F Muhammad

Index: Coumbe, Tristan; Lawrence, Nicholas J.; Muhammad, Faiz Tetrahedron Letters, 1994 , vol. 35, # 4 p. 625 - 628

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Citation Number: 115

Abstract

Abstract Phosphine oxides can be reduced by triethoxysilane, or more conveniently polymethylhydrosiloxane, and catalytic titanium (IV) isopropoxide and provides a system for the efficient one-pot generation of phosphonium salts; the reduction occurs with retention of configuration at phosphorus.

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