Inducibility of an enone reductase system in the fungus Beauveria sulfurescens: application in enantioselective organic synthesis

…, MF Renard, H Veschambre

Index: Fauve, Annie; Renard, Michel F.; Veschambre, Henri Journal of Organic Chemistry, 1987 , vol. 52, # 22 p. 4893 - 4897

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Citation Number: 22

Abstract

Microbiological reduction of a, P-unsaturated carbonyl compounds is studied. Inducibility of the enone redudase system of Beauveria sulfurescens is reported. The best inducer is shown to be cyclohex-Zen-1-one. An appropriate procedure using induced resting mycelium is developed to reduce substituted cyclohexenones that are shown to be unable to induce the reducing enzyme. Optically pure trans-(2R, 6R)-(-)-2, 6-dimethylcyclohexan-l-one and ...

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