Epinastine: topical ophthalmic second generation antihistamine without significant systemic side effects.
Shilpi Pradhan, Kumar Abhishek, Francis Mah
Index: Expert Opin. Drug Metab. Toxicol. 5(9) , 1135-40, (2009)
Full Text: HTML
Abstract
Epinastine is a topical ophthalmic antihistamine and a mast cell stabilizer indicated for treatment of symptoms associated with allergic conjunctivitis.The objective of this review is to provide a comprehensive overview of the pharmacology, clinical efficacy, tolerability and safety of epinastine 0.05% ophthalmic solution.Medline literature review from 1950 to 2008.Epinastine 0.05% ophthalmic solution was found to be a safe and effective medication for the relief of symptoms of allergic conjunctivitis. Epinastine demonstrates very low CNS and cardiac toxicity.
Related Compounds
Related Articles:
2015-03-01
[Biomed. Chromatogr. 29(3) , 465-74, (2015)]
2011-01-01
[PLoS ONE 6(11) , e26809, (2011)]
Differential effects of octopamine and tyramine on the central pattern generator for Manduca flight.
2009-03-01
[J. Comp. Physiol. A. Neuroethol. Sens. Neural. Behav. Physiol. 195(3) , 265-77, (2009)]
Treatment of allergic conjunctivitis: results of a 1-month, single-masked randomized study.
2010-01-01
[Eur. J. Ophthalmol. 20(5) , 811-8, (2010)]
Latent inhibition in an insect: the role of aminergic signaling.
2012-01-01
[Learn. Mem. 19(12) , 593-7, (2012)]