Biochemical and biophysical research communications

Reversible inactivation of bovine plasma amine oxidase by cysteamine and related analogs

HB Jeon, Y Jang

Index: Jeon, Heung Bae; Jang, Yujin Biochemical and Biophysical Research Communications, 2010 , vol. 403, # 3-4 p. 442 - 446

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Abstract

Cysteamine (1) was reported many years ago to reversibly inhibit lentil seedling amine oxidase, through the formation of a complex with thioacetaldehyde, the turnover product of 1. Herein, cysteamine (1) and its analogs 2-(methylamino) ethanethiol (3) and 3- aminopropanethiol (6) were found to be reversible inhibitors of bovine plasma amine oxidase (BPAO), but 2-(methylthio) ethylamine (7) was determined to be a weak ...