Tetrahedron Letters

First synthesis of 4, 5-dihydro-3 (2H)-pyridazinones via Zn-mediated hydrohydrazination

K Alex, A Tillack, N Schwarz, M Beller

Index: Alex, Karolin; Tillack, Annegret; Schwarz, Nicolle; Beller, Matthias Tetrahedron Letters, 2008 , vol. 49, # 31 p. 4607 - 4609

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Citation Number: 24

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The hydrohydrazination of 4-pentynoic acid with different arylhydrazines proceeds smoothly in the presence of zinc chloride. The domino amination–amidation sequence leads to aryl-substituted 4,5-dihydro-3( 2H)-pyridazinones. ... The hydrohydrazination of 4-pentynoic acid in the presence of zinc ...