Synthesis and in vitro leishmanicidal activity of some hydrazides and their analogues
…, S Hayat, F Kaukab, MI Choudhary, S Perveen
Index: Khan, Khalid Mohammad; Rasheed, Maimona; Ullah, Zia; Hayat, Safdar; Kaukab, Farhana; Choudhary, M. Iqbal; Ur-Rahman, Atta; Perveen, Shahnaz Bioorganic and Medicinal Chemistry, 2003 , vol. 11, # 7 p. 1381 - 1387
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Citation Number: 69
Abstract
Twenty-one hydrazides were synthesized by treating different esters with hydrazine hydrate. Substituted hydrazides were obtained by treating hydrazides with alkyl/aryl/acyl halides. Some of these compounds exhibit potential in vitro leishmanicidal activity. The structures of all the synthesized compounds were confirmed by spectroscopic analysis.
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