Microwave-assisted synthesis of unnatural amino acids

DD Young, J Torres-Kolbus, A Deiters

Index: Young, Douglas D.; Torres-Kolbus, Jessica; Deiters, Alexander Bioorganic and Medicinal Chemistry Letters, 2008 , vol. 18, # 20 p. 5478 - 5480

Full Text: HTML

Citation Number: 19

Abstract

Microwave irradiation has been proven to be a useful tool in the rapid assembly of racemic unnatural amino acids in only two steps. Additional benefits of this methodology are the commercial availability of the inexpensive starting materials and the high yields and high purities of the final amino acid products.

Related Articles:

Highly Efficient Catalytic Synthesis of α??Amino Acids under Phase??Transfer Conditions with a Novel Catalyst/Substrate Pair

[Belokon, Yuri N.; Kochetkov, Konstantin A.; Churkina, Tatiana D.; Ikonnikov, Nikolai S.; Larionov, Oleg V.; Harutyunyan, Syuzanna R.; Vyskocil, Stepan; North, Michael; Kagan, Henri B. Angewandte Chemie - International Edition, 2001 , vol. 40, # 10 p. 1948 - 1951]

Method for the racemization of optically active amino acids

[Yamada, Shigeki; Hongo, Chikara; Yoshioka, Ryuzo; Chibata, Ichiro Journal of Organic Chemistry, 1983 , vol. 48, # 6 p. 843 - 846]

New synthesis of DL-α-aminoacids from t-butyl N (diphenylmethylene) oxamate

[Bazureau, J.P.; Person, D.; Corre, M. Le Tetrahedron Letters, 1989 , vol. 30, # 23 p. 3065 - 3068]

Hapalocyclamide: a novel phytotoxic hexapeptide of the cyanobacterium Hapalosiphon sp.

[Tetrahedron Letters, , vol. 53, # 8 p. 977 - 979]

Synthesis of α-amino acids by addition of putative azido radicals to α-methoxy acrylonitriles derived from aldehydes and ketones

[Clive, Derrick L. J.; Etkin, Nola Tetrahedron Letters, 1994 , vol. 35, # 16 p. 2459 - 2462]

More Articles...