Amine??Catalyzed Cascade Synthesis of 3, 4??Diunsubstituted Coumarins
…, P Wang, Q Jia, J Huang, Z Du, K Zhang…
Index: Wei, Jia; Wang, Pengcheng; Jia, Qianfa; Huang, Jiaoyao; Du, Zhiyun; Zhang, Kun; Wang, Jian European Journal of Organic Chemistry, 2013 , # 21 p. 4499 - 4502
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Citation Number: 4
Abstract
Abstract We disclose an efficient route to synthesize 3, 4-diunsubstituted coumarins through a cascade organocatalytic reaction. The reaction is catalyzed by using of a combination of benzylamine (10 mol-%) and triethylamine (10 mol-%). Various salicylaldehydes were tested, and the corresponding coumarin products were obtained in good to high yields under mild and metal-free reaction conditions.
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