Journal of Dental Research 1982-09-01

Effect of Chinese and western antimicrobial agents on selected oral bacteria.

T F Tsao, M G Newman, Y Y Kwok, A K Horikoshi

Index: J. Dent. Res. 61(9) , 1103-6, (1982)

Full Text: HTML

Abstract

The susceptibility of selected oral bacteria, including suspected periodontopathogens, to a commonly employed Chinese herbal medicine Huang-chin (HC, Scutellaria baicalensis) was tested in vitro. The minimum inhibitory concentration (MIC) and minimum bactericidal concentrations (MBC) were determined. HC was also compared with tetracycline, alexidine, and stannous fluoride. HC decoction, at a concentration of 2%, was bacteriostatic in eight of 11 bacteria tested, but a concentration of 3.13% or greater was required for bactericidal effect. Among the tested bacteria, Bacteroides melaninogenicus ss intermedius was the most sensitive (MIC = 1.57%, MBC = 2%); Actinomyces viscosus was the least sensitive (MIC = 6.25%, MBC = 12.5%). Tetracycline, alexidine, and SnF2 were bactericidal in vitro in all bacteria tested at concentrations lower than those used clinically.

Related Compounds

Related Articles:

Chemical interaction of alexidine and sodium hypochlorite.

2012-01-01

[J. Endod. 38(1) , 112-6, (2012)]

Quantitative high throughput screening using a primary human three-dimensional organotypic culture predicts in vivo efficacy.

2015-01-01

[Nat. Commun. 6 , 6220, (2015)]

Pan-antimicrobial failure of alexidine as a contact lens disinfectant when heated in Bausch & Lomb plastic containers: implications for the worldwide Fusarium keratitis epidemic of 2004 to 2006.

2012-07-01

[Eye Contact Lens 38(4) , 222-6, (2012)]

Amoebicidal activities of alexidine against 3 pathogenic strains of acanthamoeba.

2009-01-01

[Eye Contact Lens 35(1) , 1-5, (2009)]

Mechanism of drug failure in fusarium keratitis, 2004-2006.

2014-01-02

[N. Engl. J. Med. 370(1) , 88-9, (2014)]

More Articles...