A rational utilization of high-throughput screening affords selective, orally bioavailable 1-benzyl-3-carboxyazetidine sphingosine-1-phosphate-1 receptor agonists

JJ Hale, CL Lynch, W Neway, SG Mills…

Index: Journal of Medicinal Chemistry, , vol. 47, # 27 p. 6662 - 6665

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Citation Number: 87

Abstract

... Journal of Medicinal ... Departments of Medicinal Chemistry and Immunology and Rheumatology Research, Merck Research Laboratories, Rahway, New Jersey ... DOI: 10.1021/jm0492507. Publication Date (Web): December 3, 2004. Copyright © 2004 American Chemical Society. ...