Chemistry Letters

Facile synthesis and conversion of main skeleton of aspirochlorin to 3-aminocoumarin derivatives

C Shin, Y Nakajima, Y Sato

Index: Shin, Chung-gi; Nakajima, Yoshiharu; Sato, Yoshiaki Chemistry Letters, 1984 , p. 1301 - 1304

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Citation Number: 5

Abstract

The condensation of 1, 4-diacetyl-2, 5-piperazinedione with salicylaldehyde gave 1-acetyl- (Z)-3-salicylidene-2, 5-piperazinedione and 3-(N-acetylglycyl) aminocoumarin by ca. 1: 1 ratio. The former was readily converted with t-BuOCl into spiro [3H-benzofuran-2, 3′-(2′, 5′-dioxo)-piperazine] derivative which has a main skeleton of aspirochlorin.

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