Formation of nickeladihydropyran by oxidative addition of cyclopropyl ketone. Key intermediate in nickel-catalyzed cycloaddition.

Sensuke Ogoshi, Midue Nagata, Hideo Kurosawa

Index: J. Am. Chem. Soc. 128(6) , 5350-5351, (2006)

Full Text: HTML

Abstract

Cyclopropyl phenyl ketone underwent oxidative addition to Ni(PCy3) generated from Ni(cod)2 and PCy3 to give a nickeladihydropyran, which is a key intermediate for the Ni(0)-catalyzed homo- or heterocycloaddition to give cyclopentane compounds having two carbonyl substituents at the 1,3-position.